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Storing Compounded Semaglutide in the Fridge: How Long?

Storing Compounded Semaglutide in the Fridge: How Long?

When you start a new medication, you want to do everything right. If you’ve started your weight loss journey with compounded semaglutide, you’re probably asking, “how long does compounded semaglutide last in the fridge?”. It’s a great question, because storing your medicine the right way is super important.

This guide will give you simple, clear answers. We’ll explain how to store your medicine so it stays safe and works like it should. Getting the right treatment from Semaglutide Medics is the first step, and taking good care of your medication is the next one.

Compounded Semaglutide vs. Branded Versions

You might have heard of brand-name medicines like Ozempic or Wegovy. Compounded semaglutide is a little different. It’s a special mix made just for you by a licensed pharmacist. Because it’s custom-made, its storage rules can be different from the big brands.

Instead of an “expiration date,” your compounded medicine has a “Beyond-Use Date,” or BUD. The pharmacy that mixes your medicine decides this date. They do tests to see how long the medicine stays good and safe to use. This date is the most important one to pay attention to.

How Long Does Compounded Semaglutide Last in the Fridge?

Okay, let’s get to the main question. While you should always check the label from your pharmacy, there is a general rule you can follow. Once you start using it, compounded semaglutide lasts for about 28 to 56 days in the fridge.

Here’s a simple breakdown to help you remember:

  • Unopened Vials: If you haven’t opened the bottle yet, you can usually store it in the fridge until the BUD printed on the label.
  • Opened (In-Use) Vials: Once you use the bottle for the first time, you should plan to throw it away after about 28 to 56 days. This is true even if there is still medicine left inside.
  • Always Check Your Label: The date from your pharmacy is the most accurate one. It’s the golden rule for your specific medicine.

This time limit is there for your safety. It makes sure the medicine is strong enough to work well and, most importantly, stays clean and free of germs. So, to be safe, how long does compounded semaglutide last in the fridge? Always trust the date your pharmacy gives you. If you ever lose your instructions, you can contact us for clarification.

Top 5 Storage Tips to Keep Your Semaglutide Safe and Effective

Keeping your medicine safe is easy once you know a few simple tricks. Here are the top five tips for storing your compounded semaglutide correctly. Following these steps will help make sure every dose is a safe dose.

  • Keep it Cool, Not Cold: Your fridge should be between 36°F and 46°F (that’s 2°C to 8°C). Try not to store your medicine in the fridge door, where the temperature can change a lot when you open and close it. A shelf in the main part of the fridge is best.
  • Never, Ever Freeze It: This one is a big deal. If your semaglutide freezes, it can ruin the medicine. Freezing can break it down and make it not work anymore. If you ever find that it has frozen by accident, you should throw it away.
  • Keep it in the Dark: Light can also damage the medicine over time. The best way to protect it is to keep the vial in its original little box. This keeps it safe from the light in your fridge.
  • Label, Label, Label: When you open a new vial, grab a pen and write the date on the box. This way, you’ll never have to guess how long it has been open. It’s a simple trick that makes a big difference.
  • Look Before You Use: Each time you get ready to take your dose, take a quick look at the liquid. It should be clear and colorless. If you see any cloudiness, little floating bits, or a strange color, do not use it.

Properly managing your treatment is simple once you know the rules. Our team is here to support you through your patient portal with any questions.

Making Treatment Simple and Affordable

We know that starting a weight loss journey is a big step. We want to make it as easy and worry-free as possible. Taking care of your medication is part of that, and it helps protect the investment you’re making in your health.

We believe managing your health should be straightforward and affordable. That’s why our program is just $299 per month. This single price includes your doctor’s consultation, the compounded semaglutide prescription, and convenient, refrigerated shipping right to your home, so you can be sure it arrives safely.

Your Storage Questions Answered

So, let’s review the most important things to remember. Always check the Beyond-Use Date on your label. Keep your medicine in the fridge at a cool, stable temperature. And never, ever let it freeze.

To answer our big question one last time: how long does compounded semaglutide last in the fridge? Your pharmacy gives you the official date, but a safe general rule is about 28 to 56 days after you first use it. By following these simple tips, you can be confident that your medicine is safe and ready to help you on your journey.

Learn more about us and our commitment to providing safe, effective, and supportive weight loss care. We are here to help you every step of the way.

Sources:

Dr. Concetta Green, MD – Board-Certified in Internal Medicine, brings over 12 years of expertise in endocrinology and personalized weight management to help patients achieve lasting health and wellness. Specializing in modern, evidence-based approaches, including GLP-1 medications, Dr. Green guides individuals toward their health goals safely and effectively. Her compassionate care and personalized strategies empower patients to take control of their wellness journey and embrace sustainable lifestyle changes.

Sources

  • Official Patient Guide for Wegovy (semaglutide) Injections: Confirms acceptable injection sites (abdomen, thigh, upper arm), advises keeping injections at least two inches away from the belly button, and provides site hygiene and general device instructions. [Wegovy Patient Guide]
  • Novo Nordisk Professional Administration Guide (Wegovy): Details the subcutaneous route into the abdomen, thigh, or upper arm, and advises patients to rotate injection sites. [novoMEDLINK]
  • Wegovy Prescribing Information (U.S.): Notes that timing of day and injection site may be changed without dose adjustment; treatment should be administered once weekly on the same day. [Wegovy Prescribing Info]
  • Ozempic (semaglutide) – “How to Take” Guide: Reinforces injection site rotation; if using the same area, select a different spot each time. [Ozempic Guide]
  • Peer-Reviewed Literature on Lipohypertrophy and Injection Rotation: Explains how consistently rotating sites and spacing injections may lower the risk of lipohypertrophy and improve medication absorption. [PubMed Central]

Important Medical Information and Disclaimers

Medical Disclaimer

This content is for educational purposes only and should not be considered medical advice, diagnosis, or treatment guidance. The U.S. Food and Drug Administration (FDA) has not approved compounded semaglutide for weight management or any other use. Now that the national shortage has ended, federal law generally prohibits pharmacies from compounding products that are essentially copies of FDA-approved medications such as Wegovy. Compounded semaglutide may carry risks related to safety, quality, and dosing accuracy because it does not undergo FDA review for safety, effectiveness, or manufacturing standards. Always consult a qualified healthcare provider before starting or continuing any semaglutide treatment, and obtain prescriptions only for FDA-approved medications dispensed through licensed pharmacies.

Individual Results May Vary

Weight management outcomes with semaglutide can differ significantly from person to person. Clinical trial data may not predict real-world experiences. Factors that influence results include:

  • Consistency with prescribed medication use
  • Dietary habits and exercise routines
  • Metabolic differences
  • Other underlying health conditions
  • Concurrent medications

No specific outcome or result can be guaranteed.

Important Safety Information

The most commonly reported side effects of semaglutide include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Stomach pain
  • Decreased appetite
  • Indigestion
  • Belching or gas
  • Injection site reactions

These side effects are often mild and may lessen over time. Before starting semaglutide, inform your healthcare provider about all medical conditions, allergies, and medications you are currently taking. Ongoing clinical monitoring is recommended during treatment.

Warning: Semaglutide carries a boxed warning regarding the potential risk of thyroid C‑cell tumors. Do not use semaglutide if you or a family member has a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Adverse Event Reporting

If you experience negative side effects from any prescription medication, you are encouraged to report them to the U.S. Food and Drug Administration (FDA) through the MedWatch Adverse Event Reporting Program or by calling 1-800-332-1088. Adverse events may also be reported directly to the medication manufacturer.

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